With the availability of tailored recombinant proteins and the opportunity to produce high amounts of monoclonal antibodies new diagnostic applications have emerged and many therapeutic perspectives eg in the treatment of multiple sclerosis and of cancer are being discussed today. Basically recombinant antibodies are monoclonal antibodies generated in vitro using synthetic genes the technology involves recovering antibody genes from source cells amplifying and cloning the genes into an appropriate phage vector introducing the vector into a host bacteria yeast or mammalian cell lines and achieving expression of . During the past two decades there have been numerous attempts at using animals in order to produce recombinant human proteins and monoclonal antibodies however it is only recently that the first two therapeutic agents isolated from the milk of transgenic animals c1 inhibitor ruconest and . The sciences behind the rise of biotechnology monoclonal antibodies this makes them a good delivery tool for inserting foreign genes into organism a process that is critical to producing recombinant dna and multiplying genes of interest they are also used to develop dna vaccines. Volume 5a recombinant proteins monoclonal antibodies and therapeutic genes volume 5b genomics volume 6 products of primary metabolism volume 7 products of secondary metabolism volumes 8a and b biotransformations i and i1 volumes l l a and b environmental processes volume 12 legal economic and ethical dimensions a multi volume comprehensive
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